• <mark id="l0x4h"></mark>

      <u id="l0x4h"></u>
        <ins id="l0x4h"></ins>

      1. <bdo id="l0x4h"></bdo>
      2. HP-PRRSV人工感染后豬血清病毒載量和體重增長的變化規律
        DOI:
        作者:
        作者單位:

        作者簡介:

        通訊作者:

        中圖分類號:

        基金項目:

        國家自然科學基金重點項目(31930104);武漢市應用基礎前沿項目(2018020401011306)


        Changes of viremia and weight gain in pigs after HP-PRRSV artificial infection
        Author:
        Affiliation:

        Fund Project:

        • 摘要
        • |
        • 圖/表
        • |
        • 訪問統計
        • |
        • 參考文獻
        • |
        • 相似文獻
        • |
        • 引證文獻
        • |
        • 資源附件
        • |
        • 文章評論
          摘要:

          為研究高致病性豬繁殖與呼吸綜合征病毒(high pathogenic-porcine reproductive and respiratory syndrome virus,HP-PRRSV)感染豬后其血清病毒載量和體重增長的變化規律,以大白豬和通城豬的高代橫交群體中72頭健康仔豬為研究對象進行HP-PRRSV人工感染,觀察臨床癥狀,并在感染前和感染后第4、7、11、14、21、28、35 天進行空腹采血、體重稱量、血清分離以及病毒載量檢測。結果顯示:在感染第0~4天體重增長速度緩慢,第4~21天體重一直呈負增長、第7~11天體重減少量達最大值、第21~35天體重呈正增長;病毒載量在感染第4天達到峰值并持續到第7天,第7~35天病毒載量逐漸下降至6.62 lg copies/mL;感染第7天出現死亡,死亡個體主要集中在7~14 d,在第10天出現死亡高峰,第19天后基本穩定;依據第14天存活與否,將試驗豬分為抗病和易感2個組,抗病組的病毒載量在第4、7、11天均顯著低于易感組(P<0.05),該組的體重增長量在第4~7、7~11、11~14天均顯著高于易感組(P<0.05)。上述結果表明,在感染過程中體重增長和病毒載量2個性狀可作為預測PRRS抗病性的指示性狀。

          Abstract:

          High pathogenic-porcine reproductive and respiratory syndrome (HP-PRRS) has caused great economic losses to pig industry in China. In order to study the changes of serum viremia and body weight gain in pigs after HP-PRRSV (HP-PRRS Virus) infection,72 healthy piglets from a large white pigs and Tongcheng pigs crossed population were selected and infected with HP-PRRSV. The clinical symptoms were observed,weight was measured,blood samples were collected,serum was separated and viremia was measured on 0,4,7,11,14,21,28,35 dpi (days post infection). The results showed that the growth rate of body weight was slow at 4 dpi,the body weight increased negatively from 4 to 21 dpi,the loss of weight reached the maximum from 7 to 11 dpi,the body weight increased positively and the growth increased gradually from 21 to 35 dpi. Viremia peaked on 4 dpi and lasted until 7 dpi,and decreased to 6.62 log10 copies/mL from 7 dpi to 35 dpi. Death occurred from 7 dpi,and the dead individuals were mainly concentrated from 7 to 14 dpi. The death peak appeared on 10 dpi,and the number of dead individuals was basically stable after 19 dpi. According to the survival on 14 dpi,the pigs were divided into two groups:disease-resistant and susceptible group. The viremia of the disease-resistant group was significantly lower than that in the susceptible group on 4,7,11 dpi (P<0.05),and the weight gain of the disease-resistant group was significantly higher than that of the susceptible group on 4-7 dpi,7-11 dpi,and 11-14 dpi (P<0.05). The above results suggested that body weight gain and viremia could be used as indicators to predict the resistance of PRRS.

          參考文獻
          相似文獻
          引證文獻
        引用本文

        高國麗,官凱鋒,孟向閣,王媛,周翔,劉榜. HP-PRRSV人工感染后豬血清病毒載量和體重增長的變化規律[J].華中農業大學學報,2020,39(5):56-61

        復制
        分享
        文章指標
        • 點擊次數:
        • 下載次數:
        • HTML閱讀次數:
        • 引用次數:
        歷史
        • 收稿日期:2020-03-25
        • 最后修改日期:
        • 錄用日期:
        • 在線發布日期: 2020-10-05
        • 出版日期:
        牌九游戏