食品安全檢驗和臨床診斷與人們健康息息相關,如何有效地提高食品安全檢測和臨床診斷能力一直是各界所關注的重點。其中,快速檢測作為一種高效方便的檢測方式被認為是突破這一難題的重要手段。磁弛豫(Magnetic Relaxation Switching, MRS) 生物傳感器因其優良的分析性能、簡便的分析流程,已經成為快速檢測的新方法、新工具。為提高磁弛豫傳感器的性能,國內外研究者在發掘有效的信號轉化機制、構建新型納米磁探針、開發高效的信號放大系統以及提高傳感器穩定性等方面開展了大量的研究工作,有力地推動了該技術在快速檢測領域的發展。本文圍繞磁弛豫生物傳感器的傳感機制、最新研究進展和應用領域展開了綜述。
Food safety analysis and clinical diagnosis are closely related to people"s health. How to improve the ability of food safety analysis and clinical diagnosis have always been the focus of all over the world. As an efficient and convenient method, rapid detection has been considered as an important means to break through this problem. And magnetic relaxation switching (MRS) biosensor has become a new tool for rapid detection due to its excellent analytical performance and simple analysis process, which has been used in the field of public health. In order to improve the performance of the MRS biosensors, researchers have done a lot of works such as exploring effective signal conversion mechanism, constructing new nanometer magnetic probe, developing efficient signal amplification system and improving the stability of the sensor, which has greatly promoted the development of rapid detection. In this paper, different sensing mechanisms, recent research progress and applications of MRS biosensors are reviewed.